Preheat the oven to 400°F (200°C).
Prepare the jalapeños by slicing them in half lengthwise and removing the seeds.
In a bowl, combine the cream cheese, shredded cheddar cheese, garlic powder, onion powder, salt, and pepper.
Fill each jalapeño half with the cheese mixture.
Wrap each filled jalapeño half with a slice of bacon, securing it with a toothpick if necessary.
Arrange the wrapped poppers on a baking sheet lined with parchment paper.
Bake in the preheated oven for 25-30 minutes or until the bacon is crispy.
Remove from the oven and let them cool slightly before serving.